No, comercial IPs are fine. You’ll have trouble with some of them - Digital Ocean is a notorious example - where the provider itself blocks outbound port 25 and there’s nothing you can do. I think DO only does that for new accounts.

I myself am running it on Linode - it did get purchased by Akamai a couple of years ago, so I can no longer blindly recommend it - but so far it’s been working fine. One thing I did recently discover was the ability to request a /56 block on Linode - my pre-assigned IPv6 got blacklisted somewhere as at least the whole /64 and simply generating another IP from the same /64 did not help. Getting a fresh block solved it for me, though, and now I know that if this /56 gets blacklisted - it’s my fault. Unless, of course, I get caught up in a /48… 😳

You won’t be able to host email on a residential IP - all of them are on a permanent blacklist. I understand the money argument - and it’s a real argument - but host your own email is just so cool!

And the other time I thought to myself - hey, let’s be nice! And so I was nice. The driver in the car in front kept reading whatever he was reading on his bloody phone and nobody moved till next light :)